abstract：:Packed bed cultivation systems have potential for widespread application in solid-state cultivation (SSC), but they are poorly characterized. The effects of particle size and substrate loading on the growth of Rhizopus oligosporus on sago-beads in packed bed bioreactors were investigated. Pressure drop and protein wer...

journal_title：Biotechnology advances

authors： Gumbira-Sa'id E,Greenfield PF,Mitchell DA,Doelle HW

更新日期：1993-01-01 00:00:00

abstract：:During a tempe fermentation the concentrations of linoleic, and alpha-linolenic acids (ALA) decreased while the concentration of oleic acid increased. During fatty acid synthesis Rhizopus sp. produced only gamma-linolenic acid (GLA) instead of ALA. The amount of GLA in tempe were influenced by varying external paramet...

journal_title：Biotechnology advances

authors： Bisping B,Hering L,Baumann U,Denter J,Keuth S,Rehm HJ

更新日期：1993-01-01 00:00:00

abstract：:Despite their widespread use in patients with acute myocardial infarction, all currently available thrombolytic agents suffer from a number of significant limitations, including resistance to reperfusion, the occurrence of acute coronary reocclusion and bleeding complications. Furthermore, the therapeutic use of plasm...

journal_title：Biotechnology advances

authors： Lijnen HR,Collen D

更新日期：1993-01-01 00:00:00

abstract：:The use of somatic embryos as artificial seeds for large scale clonal propagation of plants is close to becoming a reality. The quality of the artificial seed depends on the temporal, quantitative and qualitative supply of growth regulator and nutrients along with an optimal physical environment. Desiccation of somati...

journal_title：Biotechnology advances

authors： Senaratna T

更新日期：1992-01-01 00:00:00

abstract：:This review elaborates on the recent development of microbial sterol biotransformation systems. Particular emphasis is laid on the new enzymatic approach investigating the cleavage of sterol side chain. New developments in the area of immobilized cell system and use of organic media along with recent reviews on side c...

journal_title：Biotechnology advances

authors： Ahmad S,Garg SK,Johri BN

更新日期：1992-01-01 00:00:00

abstract：:Many advantages have been claimed over the years for the use of immobilised cells, both as enzyme systems and as whole viable cell systems for complete fermentation reactions. However, few of the claims have been fully substantiated, and may not even be entirely justified. Most research is involved with single applica...

journal_title：Biotechnology advances

authors： Dervakos GA,Webb C

更新日期：1991-01-01 00:00:00

abstract：:Developments in plant genetic engineering technology will shortly permit the commercial introduction of transgenic crop varieties resistant to a number of non-selective herbicides. High levels of tolerance have been achieved both by overexpression of a target protein and by modification of that target to an insensitiv...

journal_title：Biotechnology advances

authors： Quinn JP

更新日期：1990-01-01 00:00:00

abstract：:Bacteria produce a large number of different halogenated secondary metabolites. Haloperoxidases are believed to be the enzymes responsible for the halogenation reaction. Two classes of haloperoxidases, heme and nonheme, were isolated from different bacteria and their role in the biosynthesis of halogenated secondary m...

journal_title：Biotechnology advances

authors： Van Pée KH

更新日期：1990-01-01 00:00:00

abstract：:The aldopentose D-xylose is one of the most abundant sugars in plant biomass and its efficient microbial utilization is of fundamental importance in the overall bioconversion of lignocellulosic materials into liquid fuels and chemicals. The discovery of pentose-fermenting yeasts in the early 1980's led to world wide i...

journal_title：Biotechnology advances

authors： Webb SR,Lee H

更新日期：1990-01-01 00:00:00

abstract：:The yeast, Saccharomyces cerevisiae is currently used for the production of recombinant DNA-generated proteins derived from a variety of eukaryotic organisms. The applications of a yeast-based technology in the production of proteins for pharmaceutical and industrial purposes is discussed including current methods for...

journal_title：Biotechnology advances

authors： Martin CE,Scheinbach S

更新日期：1989-01-01 00:00:00

abstract：:Malolactic fermentation (MLF) in wine can be accomplished by relying on the natural microflora or by inducing through inoculation of a specific strain(s) of malolactic bacteria, primarily strains of Leuconostoc oenos. Problems with inducing MLF include intrinsic factors of the grape must such as pH, presence of sulfur...

journal_title：Biotechnology advances

authors： Edwards CG,Beelman RB

更新日期：1989-01-01 00:00:00

abstract：:Tissue maceration was generally elucidated by the action of endo-polygalacturonase and endo-pectate or -pectin lyase (endo-PAL or -PNL). In a process of screening of Erwinia and Pseudomonas strains for enzymatic pulping of pectocellulosic bast fibers, it was found that their PAL productivity was not completely related...

journal_title：Biotechnology advances

authors： Kobayashi Y,Komae K,Tanabe H,Matsuo R

更新日期：1988-01-01 00:00:00

abstract：:One of the major bottlenecks in automation and process control of industrial bioprocesses is the lack of suitable sensing devices to accurately measure the concentrations of biomolecules. The measurement of ions (e.g., H(+), NH(4)(+)) and gases (e.g., O(2), CO(2), NH(3)) using standard ion-selective and gas sensing el...

journal_title：Biotechnology advances

authors： Graham A,Moo-Young M

更新日期：1985-01-01 00:00:00

abstract：:Although almost every U.S. pulp mill has a biological wastewater treatment system, these systems based on bacteria, are largely ineffective in the removal of color. For this reason, we have attempted to utilize Phanerochaete chrysosporium, a fungus known to degrade lignin, as the primary organism in a novel waste trea...

journal_title：Biotechnology advances

authors： Joyce TW,Chang H,Campbell AG Jr,Gerrard ED,Kirk TK

更新日期：1984-01-01 00:00:00

abstract：:New developments in magnetic labelling techniques for cells and microspheres have extended the useful range of magnetic separation, particularly high gradient magnetic separation, into biotechnical areas. The basic magnetic principles involved are reviewed and representative samples of labelling techniques and results...

journal_title：Biotechnology advances

authors： Dunlop EH,Feiler WA,Mattione MJ

更新日期：1984-01-01 00:00:00

abstract：:For both nitrogen and carbon metabolism there exist specific regulatory mechanisms to enable cells to assimilate a wide variety of nitrogen and carbon sources. Superimposed are regulatory circuits, the so called nitrogen and carbon catabolite regulation, to allow for selective use of "rich" sources first and "poor" so...

journal_title：Biotechnology advances

authors： Hütter R,Niederberger P

更新日期：1983-01-01 00:00:00